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Bird Flu Facts
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What is avian influenza
(bird flu)?
What is the bird flu virus that has been reported in Asia and Europe? How does bird flu spread among birds?
Where have
human cases of bird flu been detected?
Does the bird flu virus
infect humans?
Does the
bird flu virus spread easily from birds to humans?
How do people become infected with bird flu viruses?
What are
the symptoms of bird flu in humans?
How is bird flu
detected in humans?
How is bird flu
treated in humans?
What drugs are
available for treatment?
Does the current seasonal influenza vaccine protect me from avian
influenza?
What
is the status of vaccine development and production?
What
are the implications of bird flu to human health?
Should I wear a surgical mask to prevent exposure to avian influenza?
Is it safe to
eat poultry and poultry products?
We
have a small flock of chickens. Is it safe to keep them?
Where can I buy a home test kit for contributing factors of this
condition?
What is avian influenza
(bird flu)? (top) Avian influenza,
or “bird flu”, is a contagious disease of animals caused by viruses that
normally infect only birds and, less commonly, pigs. Avian influenza
viruses are highly species-specific, but have, on rare occasions,
crossed the species barrier to infect humans.
What is the bird flu virus that has been reported in Asia and Europe? (top) Bird flu is an
influenza A virus. Also called the "H5N1 virus" that occurs mainly in
birds, is highly contagious among birds, and can be deadly to them.
Influenza
viruses are typed into 3 groups: A, B and C. Influenza A and B viruses
are a concern to humans. Only influenza A viruses can cause pandemics.
H5N1 is a subtype of influenza virus A.
Where have
human cases of bird flu been detected? (top) Human cases of
influenza A (H5N1) infection have been reported in Cambodia, China,
Indonesia, Thailand, and Vietnam.
Does the bird flu virus
infect humans? (top) Bird flu viruses
do not usually infect humans, but more than 100 confirmed cases of human
infection with bird flu viruses have occurred since 1997. The World
Health Organization (WHO) maintains situation updates and cumulative
reports of human cases of avian influenza A (H5N1).
Click here.
Does the
bird flu virus spread easily from birds to humans? (top) No. Though more
than 100 human cases have occurred in the current outbreak, this is a
small number compared with the huge number of birds affected and the
numerous associated opportunities for human exposure, especially in
areas where backyard flocks are common. It is not presently understood
why some people, and not others, become infected following similar
exposures.
How
do people become infected with the bird flu virus? (top)
Most cases of
avian influenza infection in humans have resulted from direct or close
contact with infected poultry (e.g., domesticated chicken, ducks, and
turkeys) or surfaces contaminated with secretions and excretions from
infected birds. The spread of avian influenza viruses from an ill person
to another person has been reported very rarely, and transmission has
not been observed to continue beyond one person. During an outbreak of
avian influenza among poultry, there is a possible risk to people who
have direct or close contact with infected birds or with surfaces that
have been contaminated with secretions and excretions from infected
birds.
What are
the symptoms of bird flu in humans? (top) Symptoms of
avian influenza in humans have ranged from typical human influenza-like
symptoms (fever, cough, sore throat, and muscle aches) to eye
infections, pneumonia, severe respiratory diseases (such as acute
respiratory distress syndrome), and other severe and life-threatening
complications. The symptoms of avian influenza may depend on which
specific virus subtype and strain caused the infection.
How is bird flu
detected in humans? (top) A laboratory
test is needed to confirm avian influenza in humans.
How is bird flu
treated in
humans? (top) Studies done in
laboratories suggest that the prescription medicines approved for human
influenza viruses should work in treating avian influenza infection in
humans. However, influenza viruses can become resistant to these drugs,
so these medications may not always work. Additional studies are needed
to determine the effectiveness of these medicines.
What drugs are
available for treatment? (top) Two drugs (in
the neuraminidase inhibitors class), oseltamivir (commercially known as
Tamiflu) and zanamivir (commercially known as Relenza) can reduce the
severity and duration of illness caused by seasonal influenza. The
efficacy of the neuraminidase inhibitors depends, among others, on their
early administration ( within 48 hours after symptom onset). For cases
of human infection with H5N1, the drugs may improve prospects of
survival, if administered early, but clinical data are limited. The H5N1
virus is expected to be susceptible to the neuraminidase inhibitors.
Antiviral resistance to neuraminidase inhibitors has been clinically
negligible so far but is likely to be detected during widespread use
during a pandemic. An older class
of antiviral drugs, the M2 inhibitors amantadine and rimantadine, could
potentially be used against pandemic influenza, but resistance to these
drugs can develop rapidly and this could significantly limit their
effectiveness against pandemic influenza. Some currently circulating
H5N1 strains are fully resistant to these the M2 inhibitors. However,
should a new virus emerge through re-assortment, the M2 inhibitors might
be effective. For the
neuraminidase inhibitors, the main constraints – which are substantial –
involve limited production capacity and a price that is prohibitively
high for many countries. At present manufacturing capacity, which has
recently quadrupled, it will take a decade to produce enough oseltamivir
to treat 20% of the world’s population. The manufacturing process for
oseltamivir is complex and time-consuming, and is not easily transferred
to other facilities. So far, most
fatal pneumonia seen in cases of H5N1 infection has resulted from the
effects of the virus, and cannot be treated with antibiotics.
Nonetheless, since influenza is often complicated by secondary bacterial
infection of the lungs, antibiotics could be life-saving in the case of
late-onset pneumonia. WHO regards it as prudent for countries to ensure
adequate supplies of antibiotics in advance.
Does the current seasonal influenza vaccine protect me from avian
influenza? (top) No. Influenza
vaccine for the 2005-06 season does not provide protection against avian
influenza.
What
is the status of vaccine development and production? (top)
Vaccines effective against a
pandemic virus are not yet available. Vaccines are produced each year
for seasonal influenza but will not protect against pandemic influenza.
Although a vaccine against the H5N1 virus is under development in
several countries, no vaccine is ready for commercial production and no
vaccines are expected to be widely available until several months after
the start of a pandemic.
Some clinical trials are now
under way to test whether experimental vaccines will be fully protective
and to determine whether different formulations can economize on the
amount of antigen required, thus boosting production capacity. Because
the vaccine needs to closely match the pandemic virus, large-scale
commercial production will not start until the new virus has emerged and
a pandemic has been declared. Current global production capacity falls
far short of the demand expected during a pandemic.
What are
the implications of bird flu to human health? (top) Two main risks for human health from avian influenza are
1) the risk of direct infection when the virus passes from the infected
bird to humans, sometimes resulting in severe disease; and 2) the risk
that the virus – if given enough opportunities – will change into a form
that is highly infectious for humans and spreads easily from person to
person.
Should I wear a surgical mask to prevent exposure to avian influenza?
(top) Currently,
wearing a mask is not recommended for routine use (e.g., in public) for
preventing influenza exposure. In the United States, disposable surgical
and procedure masks have been widely used in health-care settings to
prevent exposure to respiratory infections, but the masks have not been
used commonly in community settings, such as schools, businesses, and
public gatherings.
Is it safe to
eat poultry and poultry products? (top) Yes, though certain precautions should be followed in
countries currently experiencing outbreaks. In areas free of the
disease, poultry and poultry products can be prepared and consumed as
usual (following good hygienic practices and proper cooking), with no
fear of acquiring infection with the H5N1 virus. In areas experiencing outbreaks, poultry and poultry
products can also be safely consumed provided these items are properly
cooked and properly handled during food preparation. The H5N1 virus is
sensitive to heat. Normal temperatures used for cooking (70°C in all parts of the food) will kill the virus.
Consumers need to be sure that all parts of the poultry are fully cooked
(no “pink” parts) and that eggs, too, are properly cooked (no “runny”
yolks). Consumers should also be aware of the risk of
cross-contamination. Juices from raw poultry and poultry products should
never be allowed, during food preparation, to touch or mix with items
eaten raw. When handling raw poultry or raw poultry products, persons
involved in food preparation should wash their hands thoroughly and
clean and disinfect surfaces in contact with the poultry products Soap
and hot water are sufficient for this purpose. In areas experiencing outbreaks in poultry, raw eggs
should not be used in foods that will not be further heat-treated as,
for example by cooking or baking. Avian influenza is not transmitted through cooked food.
To date, no evidence indicates that anyone has become infected following
the consumption of properly cooked poultry or poultry products, even
when these foods were contaminated with the H5N1 virus.
We
have a small flock of chickens. Is it safe to keep them? (top) Yes. In the United States there is no need at present to
remove a flock of chickens because of concerns regarding avian
influenza. The U.S. Department of Agriculture monitors potential
infection of poultry and poultry products by avian influenza viruses and
other infectious disease agents.
Click here to purchase home
test kits for
contributing factors of this condition.
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